Commanders: U
48 commanders. Each has a deck guide with its most-played cards.
- U.S.Agent, John Walker
- Uchbenbak, the Great Mistake
- Uglúk of the White Hand
- Ukkima, Stalking Shadow
- Ulalek, Fused Atrocity
- Ulamog, the Ceaseless Hunger
- Ulamog, the Defiler
- Ulamog, the Infinite Gyre
- Ulasht, the Hate Seed
- Uldaros Theorix
- Ulrich of the Krallenhorde // Ulrich, Uncontested Alpha
- Ultima, Origin of Oblivion
- Ultimate Green Goblin
- Ultimecia, Temporal Threat
- Ultimecia, Time Sorceress // Ultimecia, Omnipotent
- Ultimo, Civilization's End
- Ultra Magnus, Tactician // Ultra Magnus, Armored Carrier
- Ultron the Annihilator
- Ultron, Artificial Malevolence
- Ultron, Machine Overlord
- Ultron, Unlimited
- Ultros, Obnoxious Octopus
- Umaro, Raging Yeti
- Umbris, Fear Manifest
- Umori, the Collector
- Uncle Iroh
- Unctus, Grand Metatect
- Unesh, Criosphinx Sovereign
- Ur-Drago
- Urabrask // The Great Work
- Urabrask the Hidden
- Urabrask, Heretic Praetor
- Urdnan, Dromoka Warrior
- Ureni of the Unwritten
- Ureni, the Song Unending
- Urgoros, the Empty One
- Urianger Augurelt
- Uril, the Miststalker
- Uro, Titan of Nature's Wrath
- Urtet, Remnant of Memnarch
- Urza, Chief Artificer
- Urza, Lord High Artificer
- Urza, Lord Protector
- Urza, Powerstone Prodigy
- Urza, Prince of Kroog
- Uurg, Spawn of Turg
- Uvilda, Dean of Perfection // Nassari, Dean of Expression
- Uyo, Silent Prophet